CPAMD8 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant CPAMD8.
Immunogen
Recombinant protein corresponding to amino acids of human CPAMD8.
Sequence
SDLGLNNITAKALAYGDTNCCRDGRSSKHPEENHADRRVPIGVDHVRRSVMVEAEGVPRAYTYSAFFCPSERVHISTPNKYEFQYVQR
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:10-1:20)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with CPAMD8 polyclonal antibody (Cat # PAB22542) shows strong cytoplasmic positivity in cells of tubules at 1:10-1:20 dilution. -
Gene Info — CPAMD8
Entrez GeneID
27151Protein Accession#
Q8IZJ3Gene Name
CPAMD8
Gene Alias
FLJ42058, FLJ90618, K-CAP, KIAA1283, VIP
Gene Description
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
Omim ID
608841Gene Ontology
HyperlinkGene Summary
CPAMD8 belongs to the complement component-3 (C3; MIM 120700)/alpha-2-macroglobulin (A2M; MIM 103950) family of proteins, which are involved in innate immunity and damage control. Complement components recognize and eliminate pathogens by direct binding or by mediating opsonization/phagocytosis and intracellular killing, and A2M is a broad-spectrum protease inhibitor (Li et al., 2004 [PubMed 15177561]).[supplied by OMIM
Other Designations
alpha-2 macroglobulin family protein VIP
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Interactome
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Disease
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