CLCN4 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant CLCN4.
Immunogen
Recombinant protein corresponding to amino acids of human CLCN4.
Sequence
VVSRDSERLIGFAQRRELILAIKNARQRQEGIVSNSIMYFTEEPPELPANSPHPLKLRRILNLS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with CLCN4 polyclonal antibody (Cat # PAB22540) shows strong cytoplasmic positivity in exocrine cells. -
Gene Info — CLCN4
Entrez GeneID
1183Protein Accession#
P51793Gene Name
CLCN4
Gene Alias
CLC4, ClC-4, ClC-4A, MGC163150
Gene Description
chloride channel 4
Omim ID
302910Gene Ontology
HyperlinkGene Summary
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. [provided by RefSeq
Other Designations
OTTHUMP00000022893
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