IL22RA2 polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells) with IL22RA2 polyclonal antibody (Cat # PAB22465).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with IL22RA2 polyclonal antibody (Cat # PAB22465) shows moderate cytoplasmic staining and luminal membrane positivity in tubules.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant IL22RA2.
Immunogen
Recombinant protein corresponding to amino acids of human IL22RA2.
Sequence
PNLPYRYQKEKNVSIEDYYELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPHSSYCVVAEIYQPMLDRRSQRSEERCVEIP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells) with IL22RA2 polyclonal antibody (Cat # PAB22465).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with IL22RA2 polyclonal antibody (Cat # PAB22465) shows moderate cytoplasmic staining and luminal membrane positivity in tubules. -
Gene Info — IL22RA2
Entrez GeneID
116379Protein Accession#
Q969J5Gene Name
IL22RA2
Gene Alias
CRF2-10, CRF2-S1, CRF2X, IL-22BP, MGC150509, MGC150510
Gene Description
interleukin 22 receptor, alpha 2
Omim ID
606648Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a soluble class II cytokine receptor. This protein has been shown to specifically bind to interleukin 22 (IL22), block the interaction of IL22 with its cell surface receptor, and thus inhibit IL22 activity. This protein functions as an IL22 antagonist, and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
Other Designations
OTTHUMP00000017282|OTTHUMP00000017283|OTTHUMP00000017284|class II cytokine receptor|interleukin 22-binding protein
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Interactome
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Pathway
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Disease
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