KIRREL polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with KIRREL polyclonal antibody (Cat # PAB22451) shows cytoplasmic positivity in podocytes in glomeruli.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant KIRREL.
Immunogen
Recombinant protein corresponding to amino acids of human KIRREL.
Sequence
VTLSIEPQTVQEGERVVFTCQATANPEILGYRWAKGGFLIEDAHESRYETNVDYSFFTEPVSCEVHNKVGSTNVSTLVNVHFAPRIVVDPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMVLSNSNQLLLKSVTQADA
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with KIRREL polyclonal antibody (Cat # PAB22451) shows cytoplasmic positivity in podocytes in glomeruli. -
Gene Info — KIRREL
Entrez GeneID
55243Protein Accession#
Q96J84Gene Name
KIRREL
Gene Alias
FLJ10845, MGC129542, MGC129543, NEPH1
Gene Description
kin of IRRE like (Drosophila)
Omim ID
607428Gene Ontology
HyperlinkGene Summary
NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM
Other Designations
OTTHUMP00000024055|kin of IRRE like|nephrin related
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Interactome
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Disease
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