MRPL24 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant MRPL24.
Immunogen
Recombinant protein corresponding to amino acids of human MRPL24.
Sequence
GKVVQVIRQRNWVVVGGLNTHYRYIGKTMDYRGTMIPSEAPLLHRQVKLVDPMDRKPTEIEWRFTEAG
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human colon with MRPL24 polyclonal antibody (Cat # PAB22430) shows moderate cytoplasmic positivity in glandular cells at 1:50-1:200 dilution. -
Gene Info — MRPL24
Entrez GeneID
79590Protein Accession#
Q96A35Gene Name
MRPL24
Gene Alias
FLJ20917, L24mt, MGC22737, MGC9831, MRP-L18, MRP-L24
Gene Description
mitochondrial ribosomal protein L24
Gene Ontology
HyperlinkGene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24). Sequence analysis identified two transcript variants that encode the same protein. [provided by RefSeq
Other Designations
39S ribosomal protein L24, mitochondrial|OTTHUMP00000038724|OTTHUMP00000038725
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