UFD1L polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate).
Lane 2: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells with UFD1L polyclonal antibody (Cat # PAB22428).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human smooth muscle with UFD1L polyclonal antibody (Cat # PAB22428) shows strong cytoplasmic positivity in smooth muscle cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant UFD1L.
Immunogen
Recombinant protein corresponding to amino acids of human UFD1L.
Sequence
QVESVNLQVATYSKFQPQSPDFLDITNPKAVLENALRNFACLTTGDVIAINYNEKIYELRVMETKPDKAVSIIECDMNVDFDAPLG
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate).
Lane 2: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells with UFD1L polyclonal antibody (Cat # PAB22428).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human smooth muscle with UFD1L polyclonal antibody (Cat # PAB22428) shows strong cytoplasmic positivity in smooth muscle cells. -
Gene Info — UFD1L
Entrez GeneID
7353Protein Accession#
Q92890Gene Name
UFD1L
Gene Alias
UFD1
Gene Description
ubiquitin fusion degradation 1 like (yeast)
Omim ID
601754Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq
Other Designations
UB fusion protein 1|ubiquitin fusion degradation 1-like|ubiquitin fusion degradation protein 1 homolog
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Interactome
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Disease
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