MLLT4 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with MLLT4 polyclonal antibody (Cat # PAB22418) shows moderate cytoplasmic and strong luminal membranous positivity in exocrine cells at 1:200-1:500 dilution.
Immunofluorescence
Immunofluorescent staining of human cell line U-251MG with MLLT4 polyclonal antibody (Cat # PAB22418) at 1-4 ug/mL dilution shows positivity in plasma membrane and cell junctions.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant MLLT4.
Immunogen
Recombinant protein corresponding to amino acids of human MLLT4.
Sequence
KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQ
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with MLLT4 polyclonal antibody (Cat # PAB22418) shows moderate cytoplasmic and strong luminal membranous positivity in exocrine cells at 1:200-1:500 dilution.Immunofluorescence
Immunofluorescent staining of human cell line U-251MG with MLLT4 polyclonal antibody (Cat # PAB22418) at 1-4 ug/mL dilution shows positivity in plasma membrane and cell junctions. -
Gene Info — MLLT4
Entrez GeneID
4301Protein Accession#
P55196Gene Name
MLLT4
Gene Alias
AF-6, AF6, AFADIN, FLJ34371, RP3-431P23.3
Gene Description
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
Omim ID
159559Gene Ontology
HyperlinkGene Summary
AF6 is a Ras (see HRAS; MIM 190020) target that regulates cell-cell adhesions downstream of Ras activation. It is fused with MLL (MIM 159555) in leukemias caused by t(6;11) translocations (Taya et al., 1998 [PubMed 9722616]).[supplied by OMIM
Other Designations
OTTHUMP00000017632|myeloid/lymphoid or mixed-lineage leukemia, translocated to, 4
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Interactome
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Pathway
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Disease
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