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Last updated: 2016/9/25
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MLLT4 polyclonal antibody

  • Catalog # : PAB22417
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against recombinant MLLT4.
  • Immunogen:
  • Recombinant protein corresponding to amino acids of human MLLT4.
  • Sequence:
  • ASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDIHSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQD
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (1:200-1:500)
    Western Blot (1:250-1:500)
    Immunofluorescence (1-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with MLLT4 polyclonal antibody (Cat # PAB22417) at 1:250-1:500 dilution.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of human pancreas with MLLT4 polyclonal antibody (Cat # PAB22417) shows distinct positivity in acinar luminal membranes at 1:200-1:500 dilution.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of human cell line A-431 with MLLT4 polyclonal antibody (Cat # PAB22417) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli, plasma membrane and cell junctions.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 4301
  • Gene Name:
  • MLLT4
  • Gene Alias:
  • AF-6,AF6,AFADIN,FLJ34371,RP3-431P23.3
  • Gene Description:
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
  • Gene Summary:
  • AF6 is a Ras (see HRAS; MIM 190020) target that regulates cell-cell adhesions downstream of Ras activation. It is fused with MLL (MIM 159555) in leukemias caused by t(6;11) translocations (Taya et al., 1998 [PubMed 9722616]).[supplied by OMIM
  • Other Designations:
  • OTTHUMP00000017632,myeloid/lymphoid or mixed-lineage leukemia, translocated to, 4
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