AGPS polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant AGPS.
Immunogen
Recombinant protein corresponding to amino acids of human AGPS.
Sequence
KERITRECKEKGVQFAPFSTCRVTQTYDAGACIYFYFAFNYRGISDPLTVFEQTEAAAREEILANGGSLSHHHGVGKLRKQWLKESISDVGFGMLKS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Western Blot (1:250-1:500)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with AGPS polyclonal antibody (Cat # PAB22416) at 1:250-1:500 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with AGPS polyclonal antibody (Cat # PAB22416) shows strong cytoplasmic positivity in subsets of islet cells at 1:200-1:500 dilution.Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with AGPS polyclonal antibody (Cat # PAB22416) at 1-4 ug/mL dilution shows positivity in nucleoli and vesicles. -
Gene Info — AGPS
Entrez GeneID
8540Protein Accession#
O00116Gene Name
AGPS
Gene Alias
ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY, DKFZp762O2215, FLJ99755
Gene Description
alkylglycerone phosphate synthase
Gene Ontology
HyperlinkGene Summary
This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome. [provided by RefSeq
Other Designations
aging-associated protein 5|alkyl-DHAP synthase|alkyldihydroxyacetone phosphate synthase|alkyldihydroxyacetonephosphate synthase, peroxisomal
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Interactome
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Pathway
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Disease
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