GGCT polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant GGCT.
Immunogen
Recombinant protein corresponding to amino acids of human GGCT.
Sequence
NSGCKDVTGPDEESFLYFAYGSNLLTERIHLRNPSAAFFCVARLQDFKLDFGNSQGKTSQTWHGGIATIFQSPGDEVWGVVWKMNKSNLNSLDE
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:10-1:20)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with GGCT polyclonal antibody (Cat # PAB22369).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human corpus, uterine with GGCT polyclonal antibody (Cat # PAB22369) shows moderate cytoplasmic positivity in glandular cells. -
Gene Info — GGCT
Entrez GeneID
79017Protein Accession#
O75223Gene Name
GGCT
Gene Alias
C7orf24, CRF21, FLJ11717, GCTG, Ggc, MGC3077
Gene Description
gamma-glutamyl cyclotransferase
Gene Ontology
HyperlinkGene Summary
GGCT (EC 2.3.2.4) catalyzes the formation of 5-oxoproline (pyroglutamic acid) from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis (Oakley et al., 2008 [PubMed 18515354]).[supplied by OMIM
Other Designations
cytochrome c-releasing factor 21|gamma -glutamyl cyclotransferase
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