PSMB1 polyclonal antibody
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with PSMB1 polyclonal antibody (Cat # PAB22319).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with PSMB1 polyclonal antibody (Cat # PAB22319) shows distinct nuclear and cytoplasmic positivity in tubular cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant PSMB1.
Immunogen
Recombinant protein corresponding to amino acids of human PSMB1.
Sequence
SGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVGS
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with PSMB1 polyclonal antibody (Cat # PAB22319).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with PSMB1 polyclonal antibody (Cat # PAB22319) shows distinct nuclear and cytoplasmic positivity in tubular cells. -
Gene Info — PSMB1
Entrez GeneID
5689Protein Accession#
P20618Gene Name
PSMB1
Gene Alias
FLJ25321, HC5, KIAA1838, PMSB1, PSC5
Gene Description
proteasome (prosome, macropain) subunit, beta type, 1
Omim ID
602017Gene Ontology
HyperlinkGene Summary
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. [provided by RefSeq
Other Designations
macropain subunit C5|multicatalytic endopeptidase complex subunit C5|proteasome beta 1 subunit|proteasome component C5|proteasome gamma chain|proteasome subunit HC5
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