HGSNAT polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant HGSNAT.
Immunogen
Recombinant protein corresponding to amino acids of human HGSNAT.
Sequence
QALLLIHNELLWTNLTVYWKSECCYHCLFQVLVNVPQSPKAGKPSAAAASVSTQHGSILQLNDTLEEKEVCRLEYRFGEFGNYSLLVKNIHNGVSEIACDLAVN
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with HGSNAT polyclonal antibody (Cat # PAB22309).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human placenta with HGSNAT polyclonal antibody (Cat # PAB22309) shows strong cytoplasmic positivity in trophoblastic cells. -
Gene Info — HGSNAT
Entrez GeneID
138050Protein Accession#
Q68CP4Gene Name
HGSNAT
Gene Alias
DKFZp686G24175, FLJ22242, FLJ32731, HGNAT, MPS3C, TMEM76
Gene Description
heparan-alpha-glucosaminide N-acetyltransferase
Gene Ontology
HyperlinkGene Summary
This gene encodes a lysosomal acetyltransferase, which is one of several enzymes involved in the lysosomal degradation of heparin sulfate. Mutations in this gene are associated with Sanfilippo syndrome C, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. [provided by RefSeq
Other Designations
transmembrane protein 76
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Interactome
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Pathway
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