RANBP17 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant RANBP17.
Immunogen
Recombinant protein corresponding to amino acids of human RANBP17.
Sequence
MDGELSCRVFQLISLMDTGLPRCCNEKIELAILWFLDQFRKTYVGDQLQRTSKVYARMSEVLGITDDNHVLETFMT
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with RANBP17 polyclonal antibody (Cat # PAB22304) shows strong cytoplasmic positivity in tubular cells. -
Gene Info — RANBP17
Entrez GeneID
64901Protein Accession#
Q9H2T7Gene Name
RANBP17
Gene Alias
FLJ32916
Gene Description
RAN binding protein 17
Omim ID
606141Gene Ontology
HyperlinkGene Summary
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM
Other Designations
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Interactome
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Disease
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