KCND3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant KCND3.
Immunogen
Recombinant protein corresponding to amino acids of human KCND3.
Sequence
NYPSTRSPSLSSHPGLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDGLRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with KCND3 polyclonal antibody (Cat # PAB22291) shows moderate positivity in indercalated ducts in exocrine pancreas at 1:200-1:500 dilution. -
Gene Info — KCND3
Entrez GeneID
3752Protein Accession#
Q9UK17Gene Name
KCND3
Gene Alias
KCND3L, KCND3S, KSHIVB, KV4.3, MGC142035, MGC142037
Gene Description
potassium voltage-gated channel, Shal-related subfamily, member 3
Omim ID
605411Gene Ontology
HyperlinkGene Summary
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene. [provided by RefSeq
Other Designations
OTTHUMP00000013771|OTTHUMP00000013772|OTTHUMP00000063948|potassium ionic channel Kv4.3|sha1-related potassium channel Kv4.3|voltage-gated K+ channel|voltage-gated potassium channel Kv4.3
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Interactome
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Disease
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