CARD10 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human liver with CARD10 polyclonal antibody (Cat # PAB22274) shows strong cytoplasmic positivity in hepatocytes at 1:10-1:20 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant CARD10.
Immunogen
Recombinant protein corresponding to amino acids of human CARD10.
Sequence
RLDFQVCPAESLSGEELCPSSAPGAPKAQPATPGLGSRIRAIQESVGKKHCLLELGARGVRELVQNEIYPIVIHVEVTEKNVREVRGLL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:10-1:20)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human liver with CARD10 polyclonal antibody (Cat # PAB22274) shows strong cytoplasmic positivity in hepatocytes at 1:10-1:20 dilution. -
Gene Info — CARD10
Entrez GeneID
29775Protein Accession#
Q9BWT7Gene Name
CARD10
Gene Alias
BIMP1, CARMA3, MGC142219
Gene Description
caspase recruitment domain family, member 10
Omim ID
607209Gene Ontology
HyperlinkGene Summary
The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM
Other Designations
Bcl10 binding protein and activator of NFKB|CARD-containing MAGUK 3 protein|caspase recruitment domain protein 10
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Interactome
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Disease
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