CPSF3L polyclonal antibody
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with CPSF3L polyclonal antibody (Cat # PAB22137).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human stomach with CPSF3L polyclonal antibody (Cat # PAB22137) strong cytoplasmic positivity in glandular cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant CPSF3L.
Immunogen
Recombinant protein corresponding to amino acids of human CPSF3L.
Sequence
LGLAEHQLRFTCRVHLHDTRKEQETALRVYSHLKSVLKDHCVQHLPDGSVTVESVLLQAAAPSEDPGTKVLLVSWTYQDEELGSFLTSLLKKG
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with CPSF3L polyclonal antibody (Cat # PAB22137).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human stomach with CPSF3L polyclonal antibody (Cat # PAB22137) strong cytoplasmic positivity in glandular cells. -
Gene Info — CPSF3L
Entrez GeneID
54973Protein Accession#
Q5TA45Gene Name
CPSF3L
Gene Alias
CPSF73L, FLJ13294, FLJ20542, INT11, INTS11, RC-68, RC68
Gene Description
cleavage and polyadenylation specific factor 3-like
Omim ID
611354Gene Ontology
HyperlinkGene Summary
The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM
Other Designations
OTTHUMP00000044092|integrator complex subunit 11|related to CPSF subunits 68 kDa
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Interactome
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Disease
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