AMPD1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant AMPD1.
Immunogen
Recombinant protein corresponding to amino acids of human AMPD1.
Sequence
AEEKQIDDAMRNFAEKVFASEVKDEGGRQEISPFDVDEICPISHHEMQAHIFHLETLSTSTEARRKKRFQGRKTVNLSIPL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human skeletal muscle with AMPD1 polyclonal antibody (Cat # PAB22103) shows strong cytoplasmic positivity in myocytes. -
Gene Info — AMPD1
Entrez GeneID
270Protein Accession#
P23109Gene Name
AMPD1
Gene Alias
MAD, MADA
Gene Description
adenosine monophosphate deaminase 1 (isoform M)
Omim ID
102770Gene Ontology
HyperlinkGene Summary
Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. [provided by RefSeq
Other Designations
OTTHUMP00000013665|OTTHUMP00000059283|adenosine monophosphate deaminase-1 (muscle)
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Interactome
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Disease
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