RC3H1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant RC3H1.
Immunogen
Recombinant protein corresponding to amino acids of human RC3H1.
Sequence
RTSKTIYQGAGPMQAMAPQGAPTKSINISDYSPYGTHGGWGASPYSPHQNIPSQGHFSERERISMSEVASHGKPLPSAEREQLRLELQQLNHQISQQTQ
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with RC3H1 polyclonal antibody (Cat # PAB22034) shows strong cytoplasmic positivity in subsets of islet cells. -
Gene Info — RC3H1
Entrez GeneID
149041Protein Accession#
Q5TC82Gene Name
RC3H1
Gene Alias
KIAA2025, RNF198, ROQUIN
Gene Description
ring finger and CCCH-type zinc finger domains 1
Omim ID
609424Gene Ontology
HyperlinkGene Summary
RC3H1, or roquin, encodes a highly conserved member of the RING type ubiquitin ligase protein family (Vinuesa et al., 2005 [PubMed 15917799]). The roquin protein is distinguished by the presence of a CCCH zinc finger found in RNA-binding proteins, and localization to cytosolic RNA granules implicated in regulating mRNA translation and stability.[supplied by OMIM
Other Designations
OTTHUMP00000060492|roquin
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