PTAFR polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human colon with PTAFR polyclonal antibody (Cat # PAB22031) strong cytoplasmic positivity in glandular cells.
Immunofluorescence
Immunofluorescent staining of human cell line U-251MG with PTAFR polyclonal antibody (Cat # PAB22031) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli, plasma membrane and vesicles.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant PTAFR.
Immunogen
Recombinant protein corresponding to amino acids of human PTAFR.
Sequence
LDSTNTVPDSAGSGNVTRCFEHYEKGS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human colon with PTAFR polyclonal antibody (Cat # PAB22031) strong cytoplasmic positivity in glandular cells.Immunofluorescence
Immunofluorescent staining of human cell line U-251MG with PTAFR polyclonal antibody (Cat # PAB22031) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli, plasma membrane and vesicles. -
Gene Info — PTAFR
Entrez GeneID
5724Protein Accession#
P25105Gene Name
PTAFR
Gene Alias
PAFR
Gene Description
platelet-activating factor receptor
Omim ID
173393Gene Ontology
HyperlinkGene Summary
PTAFR shows structural characteristics of the rhodopsin (MIM 180380) gene family and binds platelet-activating factor (PAF). PAF is a phospholipid (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes.[supplied by OMIM
Other Designations
OTTHUMP00000004040|OTTHUMP00000004041
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Interactome
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Pathway
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Disease
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