BCLAF1 polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against recombinant BCLAF1.
Immunogen
Recombinant protein corresponding to amino acids of human BCLAF1.
Sequence
QKSPEIHRRIDISPSTLRKHTRLAGEERVFKEENQKGDKKLRCDSADLRHDIDRRRKERSKERGDSKGSRESSGSRKQEKTPKDYKEYKSYKDDSKHKREQDHSRSSSSSASPSSPSSR
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebral cortex with BCLAF1 polyclonal antibody (Cat # PAB21902) shows strong nuclear positivity in neuronal cells and glial cells at 1:50-1:200 dilution.Immunofluorescence
Immunofluorescent staining of human cell line A-431 with BCLAF1 polyclonal antibody (Cat # PAB21902) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli. -
Gene Info — BCLAF1
Entrez GeneID
9774Protein Accession#
Q9NYF8Gene Name
BCLAF1
Gene Alias
BTF, KIAA0164, bK211L9.1
Gene Description
BCL2-associated transcription factor 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
Bcl-2-associated transcription factor
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