ARID4B polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant ARID4B.
Immunogen
Recombinant protein corresponding to amino acids of human ARID4B.
Sequence
DNNGKEESKIDHLTNNRNDLISKEEQNSSSLLEENKVHADLVISKPVSKSPERLRKDIEVLSEDTDYEEDEVTKKRKDVKKDTTDKSSKPQIKRGKR
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human placenta with ARID4B polyclonal antibody (Cat # PAB21892) shows moderate nuclear positivity in decidual cells at 1:50-1:200 dilution. -
Gene Info — ARID4B
Entrez GeneID
51742Protein Accession#
Q4LE39Gene Name
ARID4B
Gene Alias
BCAA, BRCAA1, DKFZp313M2420, MGC163290, RBBP1L1, RBP1L1, SAP180
Gene Description
AT rich interactive domain 4B (RBP1-like)
Omim ID
609696Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq
Other Designations
AT rich interactive domain 4B|OTTHUMP00000037596|RBP1-like protein|Rb-binding protein homolog|SIN3A-associated protein 180|breast cancer-associated antigen 1|breast carcinoma-associated antigen|retinoblastoma binding protein 1-like 1|retinoblastoma-bindin
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Interactome
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Disease
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