Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells) with RAB14 polyclonal antibody (Cat # PAB21798) at 1:250-1:500 dilution.
RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al., 2004 [PubMed 15004230]).[supplied by OMIM
F protein-binding protein 1,GTPase Rab14,OTTHUMP00000022008,bA165P4.3 (member RAS oncogene family),small GTP binding protein RAB14