RAB3GAP2 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human bronchus with RAB3GAP2 polyclonal antibody (Cat # PAB21794) shows strong cytoplasmic positivity in respiratory epithelial cells.
Immunofluorescence
Immunofluorescent staining of human cell line U-251 MG with RAB3GAP2 polyclonal antibody (Cat # PAB21794) at 1-4 ug/mL dilution shows positivity in cytoplasm.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant RAB3GAP2.
Immunogen
Recombinant protein corresponding to amino acids of human RAB3GAP2.
Sequence
TYEIPRHPGVTEQNEELSILYPAAIVTIDGFSLFQSLRACRNQVAKAAASGNENIQPPPLAYKKWGLQDIDTIIDHASVGIMTLSPFDQMKTA
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human bronchus with RAB3GAP2 polyclonal antibody (Cat # PAB21794) shows strong cytoplasmic positivity in respiratory epithelial cells.Immunofluorescence
Immunofluorescent staining of human cell line U-251 MG with RAB3GAP2 polyclonal antibody (Cat # PAB21794) at 1-4 ug/mL dilution shows positivity in cytoplasm. -
Gene Info — RAB3GAP2
Entrez GeneID
25782Protein Accession#
Q9H2M9Gene Name
RAB3GAP2
Gene Alias
DKFZp434D245, FLJ14579, KIAA0839, RAB3-GAP150, RAB3GAP150, p150
Gene Description
RAB3 GTPase activating protein subunit 2 (non-catalytic)
Gene Ontology
HyperlinkGene Summary
Members of the RAB3 protein family (see RAB3A; MIM 179490) are implicated in Ca(2+)-dependent exocytosis. RAB3GAP, which is involved in regulation of RAB3 activity, is a heterodimeric complex consisting a 130-kD catalytic subunit (RAB3GAP1; MIM 602536) and a 150-kD noncatalytic subunit (RAB3GAP2) (Nagano et al., 1998 [PubMed 9733780]).[supplied by OMIM
Other Designations
rab3 GTPase-activating protein, non-catalytic subunit|rab3 GTPase-activating protein, non-catalytic subunit (150kD)|rab3 GTPase-activating protein, non-catalytic subunit (RAB3-GAP150)
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Interactome
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