ARFGEF2 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human small intestine with ARFGEF2 polyclonal antibody (Cat # PAB21791) shows distinct cytoplasmic positivity in glandular cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant ARFGEF2.
Immunogen
Recombinant protein corresponding to amino acids of human ARFGEF2.
Sequence
KPIQSKPQSPVIQAAAVSPKFVRLKHSQAQSKPTTPEKTDLTNGEHARSDSGKVSTENGDAPRERGSSLSGTDDGAQEVVKDILEDVVTSAIKAAEKHGLTEPERVLGELECQECAIPPGVDENSQTNGI
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human small intestine with ARFGEF2 polyclonal antibody (Cat # PAB21791) shows distinct cytoplasmic positivity in glandular cells. -
Gene Info — ARFGEF2
Entrez GeneID
10564Protein Accession#
Q9Y6D5Gene Name
ARFGEF2
Gene Alias
BIG2, FLJ23723, dJ1164I10.1
Gene Description
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
Gene Ontology
HyperlinkGene Summary
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq
Other Designations
ADP-ribosylation factor guanine nucleotide-exchange factor 2|OTTHUMP00000031231|brefeldin A-inhibited guanine nucleotide-exchange protein 2
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