FAT1 polyclonal antibody

Catalog # PAB21615

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Size:100 uL
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining of human placenta with FAT1 polyclonal antibody (Cat # PAB21615) shows strong cytoplasmic positivity in decidual cells at 1:20-1:50 dilution.

  • Specification

    Product Description

    Rabbit polyclonal antibody raised against recombinant FAT1.

    Immunogen

    Recombinant protein corresponding to amino acids of human FAT1.

    Sequence

    NFQRALRNILGVRRNDIQIVSLQSSEPHPHLDVLLFVEKPGSAQISTKQLLHKINSSVTDIEEIIGVRILNVFQKLCAGLDCPWKFCDEKVSVDESVMSTHSTARLSFVTPRHHRAAVCLCKEGRCP

    Host

    Rabbit

    Reactivity

    Human

    Form

    Liquid

    Purification

    Antigen affinity purification

    Isotype

    IgG

    Recommend Usage

    Immunohistochemistry (1:20-1:50)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)

    Storage Instruction

    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical staining of human placenta with FAT1 polyclonal antibody (Cat # PAB21615) shows strong cytoplasmic positivity in decidual cells at 1:20-1:50 dilution.
  • Gene Info — FAT1

    Entrez GeneID

    2195

    Protein Accession#

    Q14517

    Gene Name

    FAT1

    Gene Alias

    CDHF7, FAT, ME5, hFat1

    Gene Description

    FAT tumor suppressor homolog 1 (Drosophila)

    Omim ID

    600976

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq

    Other Designations

    FAT tumor suppressor 1|cadherin ME5|cadherin family member 7|cadherin-related tumor suppressor

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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