LRBA polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human rectum with LRBA polyclonal antibody (Cat # PAB21593) strong cytoplasmic positivity in glandular cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant LRBA.
Immunogen
Recombinant protein corresponding to amino acids of human LRBA.
Sequence
GGWRVWVDTLSITHSKVTFEIHKENLANIFREQQGKVDEEIGLCSSTSVQAASGIRRDINVSVGSQQPDTKDSPVCPHFTTNGNENSSIEKTSSLESASNIELQTTNTSYEEMKAEQENQELPDEGTLEETL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human rectum with LRBA polyclonal antibody (Cat # PAB21593) strong cytoplasmic positivity in glandular cells. -
Gene Info — LRBA
Entrez GeneID
987Protein Accession#
P50851Gene Name
LRBA
Gene Alias
BGL, CDC4L, DKFZp686A09128, DKFZp686K03100, DKFZp686P2258, FLJ16600, FLJ25686, LAB300, LBA, MGC72098
Gene Description
LPS-responsive vesicle trafficking, beach and anchor containing
Omim ID
606453Gene Ontology
HyperlinkGene Summary
Patients with Chediak-Higashi syndrome (CHS1; MIM 214500) suffer from a systemic immunodeficiency involving defects in polarized trafficking of vesicles in a number of immune system cell types. In mouse, this syndrome is reproduced in strains with a mutation in the 'beige' gene that results in proteins lacking the BEACH (beige and CHS1) domain and C-terminal WD repeats. LRBA contains key features of both beige/CHS1 and A kinase anchor proteins (AKAPs; see MIM 602449).[supplied by OMIM
Other Designations
cell division cycle 4-like|vesicle trafficking, beach and anchor containing
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Interactome
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Disease
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