NEFM polyclonal antibody

Catalog # PAB21539

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Size:100 uL
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Application

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining of human cerebellum with NEFM polyclonal antibody (Cat # PAB21539) shows moderate cytoplasmic positivity in Purkinje cells.

Immunofluorescence
Application

Immunofluorescence

Immunofluorescent staining of human cell line A-431 shows positivity in cytoplasm.
Using NEFM polyclonal antibody (Cat # PAB21539).

  • Specification

    Product Description

    Rabbit polyclonal antibody raised against recombinant NEFM.

    Immunogen

    Recombinant protein corresponding to amino acids of human NEFM.

    Sequence

    YIEKVHYLEQQNKEIEAEIQALRQKQASHAQLGDAYDQEIRELRATLEMVNHEKAQVQLDSDHLEEDIHRLKERFEEEARLRDDTEAAIRALRKDIEEASLVKVELDKKVQSLQDEVAFLRSNH

    Host

    Rabbit

    Reactivity

    Human

    Form

    Liquid

    Purification

    Antigen affinity purification

    Isotype

    IgG

    Recommend Usage

    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)

    Storage Instruction

    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunohistochemical staining of human cerebellum with NEFM polyclonal antibody (Cat # PAB21539) shows moderate cytoplasmic positivity in Purkinje cells.

    Immunofluorescence

    Immunofluorescent staining of human cell line A-431 shows positivity in cytoplasm.
    Using NEFM polyclonal antibody (Cat # PAB21539).
  • Gene Info — NEFM

    Entrez GeneID

    4741

    Protein Accession#

    P07197

    Gene Name

    NEFM

    Gene Alias

    NEF3, NF-M, NFM

    Gene Description

    neurofilament, medium polypeptide

    Omim ID

    162250

    Gene Ontology

    Hyperlink

    Gene Summary

    Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq

    Other Designations

    neurofilament triplet M protein|neurofilament, medium polypeptide 150kDa|neurofilament-3 (150 kD medium)

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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