GARNL4 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant GARNL4.
Immunogen
Recombinant protein corresponding to amino acids of human GARNL4.
Sequence
MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFFEMLEKMQGIKLEEQKPGPQKNKDDYIPYPSIDEVVEKGGPYPQVI
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human colon with GARNL4 polyclonal antibody (Cat # PAB21479) shows strong cytoplasmic, membranous and nuclear positivity in glandular cells at 1:50-1:200 dilution. -
Gene Info — GARNL4
Entrez GeneID
23108Protein Accession#
Q684P5Gene Name
GARNL4
Gene Alias
DKFZp686O238, KIAA1039, RAP1GA3, Rap1GAP2
Gene Description
GTPase activating Rap/RanGAP domain-like 4
Gene Ontology
HyperlinkGene Summary
This gene encodes a GTPase-activating protein that activates the small guanine-nucleotide-binding protein Rap1 in platelets. The protein interacts with synaptotagmin-like protein 1 and Rab27 and regulates secretion of dense granules from platelets at sites of endothelial damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
GTPase activating RANGAP domain-like 4|Rap1 GTPase activating protein IIIa|Rap1 GTPase activating protein IIIb
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Interactome
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Disease
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