NUP88 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant NUP88.
Immunogen
Recombinant protein corresponding to amino acids of human NUP88.
Sequence
QLLTRNVVFGLGGELFLWDGEDSSFLVVRLRGPSGGGEEPALSQYQRLLCINPPLFEIYQVLLSPTQHHVALIGIKGLMVLELPKRWGKNSEFEGGKSTVNCSTTPVAERFFTSSTSLTLKHAAWYPSEILDPHVV
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:10-1:20)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebral cortex with NUP88 polyclonal antibody (Cat # PAB21456) shows strong nuclear positivity in neuronal and glial cells.Immunofluorescence
Immunofluorescent staining of human cell line U-251MG with NUP88 polyclonal antibody (Cat # PAB21456) at 1-4 ug/mL dilution shows positivity in nuclei but not nucleoli. -
Gene Info — NUP88
Entrez GeneID
4927Protein Accession#
Q99567Gene Name
NUP88
Gene Alias
MGC8530
Gene Description
nucleoporin 88kDa
Omim ID
602552Gene Ontology
HyperlinkGene Summary
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. [provided by RefSeq
Other Designations
karyoporin|nuclear pore complex protein 88
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