OSBP2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant OSBP2.
Immunogen
Recombinant protein corresponding to amino acids of human OSBP2.
Sequence
SRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSAPGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITV
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:1000-1:2500)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with OSBP2 polyclonal antibody (Cat # PAB21420).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human duodenum with OSBP2 polyclonal antibody (Cat # PAB21420) strong cytoplasmic positivity in glandular cells. -
Gene Info — OSBP2
Entrez GeneID
23762Protein Accession#
Q969R2Gene Name
OSBP2
Gene Alias
ORP-4, ORP4, OSBPL1, OSBPL4
Gene Description
oxysterol binding protein 2
Omim ID
606729Gene Ontology
HyperlinkGene Summary
Oxysterols are byproducts of cholesterol that can have cytotoxic effects on many cell types. The membrane-bound protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternate transcriptional splice variants have been observed but have not been fully characterized. [provided by RefSeq
Other Designations
OSBP-related protein 4|OTTHUMP00000028525|oxysterol binding protein-like 1|oxysterol binding protein-related protein 4
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Interactome
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