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Last updated: 2016/9/25
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HSD17B4 polyclonal antibody

  • Catalog # : PAB21385
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against recombinant HSD17B4.
  • Immunogen:
  • Recombinant protein corresponding to amino acids of human HSD17B4.
  • Sequence:
  • ESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (1:50-1:200)
    Western Blot (1:250-1:500)
    Immunofluorescence (1-4 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with HSD17B4 polyclonal antibody (Cat # PAB21385) at 1:250-1:500 dilution.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of human duodenum with HSD17B4 polyclonal antibody (Cat # PAB21385) strong cytoplasmic positivity in glandular cells at 1:50-1:200 dilution.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of human cell line A-431 with HSD17B4 polyclonal antibody (Cat # PAB21385) at 1-4 ug/mL dilution shows positivity in vesicles.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 3295
  • Gene Name:
  • HSD17B4
  • Gene Alias:
  • DBP,MFE-2,SDR8C1
  • Gene Description:
  • hydroxysteroid (17-beta) dehydrogenase 4
  • Gene Summary:
  • The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. [provided by RefSeq
  • Other Designations:
  • 17-beta-HSD IV,17-beta-hydroxysteroid dehydrogenase 4,17beta-estradiol dehydrogenase type IV,3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase,D-3-hydroxyacyl-CoA dehydratase,D-bifunctional protein, peroxisomal,beta-hydroxyacyl deh
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