RNF216 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human testis with RNF216 polyclonal antibody (Cat # PAB21357) shows strong cytoplasmic positivity in developing sperm cells.
Immunofluorescence
Immunofluorescent staining of human cell line A-431 with RNF216 polyclonal antibody (Cat # PAB21357) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli and cytoplasm.
-
Specification
Product Description
Rabbit polyclonal antibody raised against recombinant RNF216.
Immunogen
Recombinant protein corresponding to amino acids of human RNF216.
Sequence
KVIILEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQQPREITNQVVPQERQPEAELGRLLFQHEFPGPAFP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human testis with RNF216 polyclonal antibody (Cat # PAB21357) shows strong cytoplasmic positivity in developing sperm cells.Immunofluorescence
Immunofluorescent staining of human cell line A-431 with RNF216 polyclonal antibody (Cat # PAB21357) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli and cytoplasm. -
Gene Info — RNF216
Entrez GeneID
54476Protein Accession#
Q9NWF9Gene Name
RNF216
Gene Alias
TRIAD3, U7I1, UBCE7IP1, ZIN
Gene Description
ring finger protein 216
Omim ID
609948Gene Ontology
HyperlinkGene Summary
This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known. [provided by RefSeq
Other Designations
ubiquitin conjugating enzyme 7 interacting protein 1
-
Interactome
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com