GCAT polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant GCAT.
Immunogen
Recombinant protein corresponding to amino acids of human GCAT.
Sequence
CLASRYGALVFMDECHATGFLGPTGRGTDELLGVMDQVTIINSTLGKALGGASGGYTTGPGPLVSLLRQRARPYLFSNSLPPAVVGCASKALDLLMGSNTIVQSMAAKTQRFRSKMEAAGFTISGA
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human small intestine with GCAT polyclonal antibody (Cat # PAB21302) shows distinct positivity in mucus of goblet cells. -
Gene Info — GCAT
Entrez GeneID
23464Protein Accession#
O75600Gene Name
GCAT
Gene Alias
KBL, MGC23053
Gene Description
glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase)
Omim ID
607422Gene Ontology
HyperlinkGene Summary
The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. [provided by RefSeq
Other Designations
2-amino-3-ketobutyrate-CoA ligase|AKB ligase|aminoacetone synthase|glycine C-acetyltransferase
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Interactome
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Pathway
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