COG5 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human colon with COG5 polyclonal antibody (Cat # PAB21288) shows strong cytoplasmic positivity in granular pattern in glandular cells.
Immunofluorescence
Immunofluorescent staining of human cell line U-251MG with COG5 polyclonal antibody (Cat # PAB21288) at 1-4 ug/mL dilution shows positivity in golgi apparatus.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant COG5.
Immunogen
Recombinant protein corresponding to amino acids of human COG5.
Sequence
SFWTNMEKLMDHIYAVCGQVQHLQKVLAKKRDPVSHICFIEEIVKDGQPEIFYTFWNSVTQALSSQFHMATNSSMFLKQAFEGEYPKLLRLYNDLWKRLQQYSQHIQGNFNASGTTDLYVD
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human colon with COG5 polyclonal antibody (Cat # PAB21288) shows strong cytoplasmic positivity in granular pattern in glandular cells.Immunofluorescence
Immunofluorescent staining of human cell line U-251MG with COG5 polyclonal antibody (Cat # PAB21288) at 1-4 ug/mL dilution shows positivity in golgi apparatus. -
Gene Info — COG5
Entrez GeneID
10466Protein Accession#
Q9UP83Gene Name
COG5
Gene Alias
GOLTC1, GTC90
Gene Description
component of oligomeric golgi complex 5
Omim ID
606821Gene Ontology
HyperlinkGene Summary
Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG5 (Ungar et al., 2002 [PubMed 11980916]).[supplied by OMIM
Other Designations
conserved oligomeric Golgi complex protein 5|golgi transport complex 1 (90 kDa subunit)
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Interactome
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Disease
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