PPP1R15A polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant PPP1R15A.
Immunogen
Recombinant protein corresponding to amino acids of human PPP1R15A.
Sequence
QPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEAEPCP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with PPP1R15A polyclonal antibody (Cat # PAB21284) shows strong cytoplasmic positivity in both exocrine glandular cells and islet cells. -
Gene Info — PPP1R15A
Entrez GeneID
23645Protein Accession#
O75807Gene Name
PPP1R15A
Gene Alias
GADD34
Gene Description
protein phosphatase 1, regulatory (inhibitor) subunit 15A
Omim ID
611048Gene Ontology
HyperlinkGene Summary
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation. [provided by RefSeq
Other Designations
growth arrest and DNA-damage-inducible 34|protein phosphatase 1, regulatory subunit 15A
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