PNPLA8 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant PNPLA8.
Immunogen
Recombinant protein corresponding to amino acids of human PNPLA8.
Sequence
DSGWLKQKNIKQAIKSLKKYSDKSAEKSPFPEEKSHIIDKEEDIGKRSLFHYTSSITTKFGDSFYFLSNHINSYFKRKEKMSQQKENE
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with PNPLA8 polyclonal antibody (Cat # PAB21270) at 1:250-1:500 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human duodenum with PNPLA8 polyclonal antibody (Cat # PAB21270) strong cytoplasmic positivity in glandular cells. -
Gene Info — PNPLA8
Entrez GeneID
50640Protein Accession#
Q9NP80Gene Name
PNPLA8
Gene Alias
IPLA2(GAMMA), IPLA2-2, IPLA2G
Gene Description
patatin-like phospholipase domain containing 8
Gene Ontology
HyperlinkGene Summary
Phospholipase A2 catalyzes cleavage of fatty acids from phospholipids, thereby regulating membrane physical properties and the release of lipid second messengers and growth factors. Phospholipase A2 activity also modulates cellular growth programs, inflammation, and ion channel function (Mancuso et al., 2000 [PubMed 10744668]).[supplied by OMIM
Other Designations
iPLA2 gamma|intracellular membrane-associated calcium-independent phospholipase A2 gamma|membrane-associated calcium-independent phospholipase A2 gamma
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Interactome
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Disease
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