Western blot analysis of PIK3CA polyclonal antibody (Cat # PAB2126) in K-562 cell line lysates (35 ug/lane). PIK3CA (arrow) was detected using the purified Polyclonal antibody.
Western Blot (Transfected lysate)
Western blot analysis of PIK3CA (arrow) using PIK3CA polyclonal antibody (Cat # PAB2126) in 293 cell line lysates transiently transfected with the PIK3CA gene (1 ug/lane). PIK3CA (arrow) was detected using the purified Polyclonal antibody.
Formalin-fixed and paraffin-embedded human breast carcinoma reacted with PIK3CA polyclonal antibody (Cat # PAB2126) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. [provided by RefSeq