Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate). Lane 2: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells with DNASE1L3 polyclonal antibody (Cat # PAB21259).
This gene encodes a member of the DNase family. The protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq
DNase I homolog protein 2,DNase gamma,LS-DNase,Liver and spleen DNase,deoxyribonuclease I-like III,deoxyribonuclease gamma