ARHGAP23 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant ARHGAP23.
Immunogen
Recombinant protein corresponding to amino acids of human ARHGAP23.
Sequence
MNLGFGDESPEPEASGRGERLGRKVAPLATTEDSLASIPFIDEPTSPSIDLQAKHVPASAVVSSAMNSAPVLGTSPSS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebellum with ARHGAP23 polyclonal antibody (Cat # PAB21244) shows strong cytoplasmic and nuclear positivity in Purkinje cells. -
Gene Info — ARHGAP23
Entrez GeneID
57636Protein Accession#
Q9P227Gene Name
ARHGAP23
Gene Alias
KIAA1501
Gene Description
Rho GTPase activating protein 23
Omim ID
610590Gene Ontology
HyperlinkGene Summary
The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 [PubMed 15254754]).[supplied by OMIM
Other Designations
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