Immunohistochemical staining of human lymph node with KCNC2 polyclonal antibody (Cat # PAB21229) shows strong cytoplasmic positivity in a subset of lymphoid cells outside reaction centra at 1:50-1:200 dilution.
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
Shaw-related voltage-gated potassium channel protein 2