ANGPT1 polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against recombinant ANGPT1.
Immunogen
Recombinant protein corresponding to amino acids of human ANGPT1.
Sequence
SNQRRSPENSGRRYNRIQHGQCAYTFILPEHDGNCRESTTDQYNTNALQRDAPHVEPDFSSQKLQHLEHVME
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with ANGPT1 polyclonal antibody (Cat # PAB21177).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human rectum with ANGPT1 polyclonal antibody (Cat # PAB21177) strong cytoplasmic positivity in glandular cells. -
Gene Info — ANGPT1
Entrez GeneID
284Protein Accession#
Q15389Gene Name
ANGPT1
Gene Alias
AGP1, AGPT, ANG1
Gene Description
angiopoietin 1
Omim ID
601667Gene Ontology
HyperlinkGene Summary
Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. [provided by RefSeq
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