GLDC polyclonal antibody
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with GLDC polyclonal antibody (Cat # PAB21084).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebral cortex with GLDC polyclonal antibody (Cat # PAB21084) shows strong cytoplasmic positivity in neuronal cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant GLDC.
Immunogen
Recombinant protein corresponding to amino acids of human GLDC.
Sequence
ILNANYMAKRLETHYRILFRGARGYVGHEFILDTRPFKKSANIEAVDVAKRLQDYGFHAPTMSWPVAGTLMVEPTESEDKAELDRFCDAMISIRQEIADIEEGRIDPRVNPLKMSPHSLTCVTSSHWDRPYSREVAAFPLPFVKPENK
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with GLDC polyclonal antibody (Cat # PAB21084).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebral cortex with GLDC polyclonal antibody (Cat # PAB21084) shows strong cytoplasmic positivity in neuronal cells. -
Gene Info — GLDC
Entrez GeneID
2731Protein Accession#
P23378Gene Name
GLDC
Gene Alias
GCE, GCSP, HYGN1, MGC138198, MGC138200, NKH
Gene Description
glycine dehydrogenase (decarboxylating)
Gene Ontology
HyperlinkGene Summary
The enzyme system for cleavage of glycine (glycine cleavage system; GCS; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). Glycine encephalopathy (GCE; MIM 605899) may be due to a defect in any one of these enzymes; see MIM 238310, MIM 238330, and MIM 238331.[supplied by OMIM
Other Designations
OTTHUMP00000044451|glycine cleavage system protein P|glycine decarboxylase P-protein|glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P)
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Interactome
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Pathway
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Disease
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