DGCR2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant DGCR2.
Immunogen
Recombinant protein corresponding to amino acids of human DGCR2.
Sequence
RFSRKCPTGWHHYEGTASCYRVYLSGENYWDAAQTCQRLNGSLATFSTDQELRFVLAQEWDQPERSFGWKDQRKLWVGYQYVITGRNRSLEGRWEVAFKGSSEVFLPPDPIFASAMSENDNVFCAQLQCFHFPTLRHHDLHSWHAESCYEKSSFLCKRSQTCVDIKDNVVDEGFYFTPK
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with DGCR2 polyclonal antibody (Cat # PAB21078) shows strong cytoplasmic positivity in islet cells at 1:20-1:50 dilution. -
Gene Info — DGCR2
Entrez GeneID
9993Protein Accession#
P98153Gene Name
DGCR2
Gene Alias
DGS-C, DKFZp686I1730, IDD, KIAA0163, LAN, SEZ-12
Gene Description
DiGeorge syndrome critical region gene 2
Omim ID
600594Gene Ontology
HyperlinkGene Summary
Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. [provided by RefSeq
Other Designations
integral membrane protein DGCR2
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Interactome
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Disease
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