SLC30A4 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human hippocampus with SLC30A4 polyclonal antibody (Cat # PAB21018) shows strong cytoplasmic positivity in glial cells at 1:10-1:20 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant SLC30A4.
Immunogen
Recombinant protein corresponding to amino acids of human SLC30A4.
Sequence
PSHLNVDYIKEALMKIEDVYSVEDLNIWSLTSGKSTAIVHIQLIPGSSSKWEEVQSKANHLLLNTFGMYRCTIQLQSYRQEVDRTCANCQ
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:10-1:20)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human hippocampus with SLC30A4 polyclonal antibody (Cat # PAB21018) shows strong cytoplasmic positivity in glial cells at 1:10-1:20 dilution. -
Gene Info — SLC30A4
Entrez GeneID
7782Protein Accession#
O14863Gene Name
SLC30A4
Gene Alias
ZNT4
Gene Description
solute carrier family 30 (zinc transporter), member 4
Omim ID
602095Gene Ontology
HyperlinkGene Summary
Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e.g., MIM 114852), alkaline phosphatases (e.g., MIM 171760), various dehydrogenases, and superoxide dismutases (e.g., MIM 147450). SLC30A4, or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop (Huang and Gitschier, 1997 [PubMed 9354792]).[supplied by OMIM
Other Designations
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Interactome
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Disease
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