SIGMAR1 polyclonal antibody
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with SIGMAR1 polyclonal antibody (Cat # PAB20993).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human small intestine with SIGMAR1 polyclonal antibody (Cat # PAB20993) shows distinct positivity in glandular cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant SIGMAR1.
Immunogen
Recombinant protein corresponding to amino acids of human SIGMAR1.
Sequence
FVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGG
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:10-1:20)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with SIGMAR1 polyclonal antibody (Cat # PAB20993).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human small intestine with SIGMAR1 polyclonal antibody (Cat # PAB20993) shows distinct positivity in glandular cells. -
Gene Info — SIGMAR1
Entrez GeneID
10280Protein Accession#
Q99720Gene Name
SIGMAR1
Gene Alias
FLJ25585, MGC3851, OPRS1, SR-BP1
Gene Description
sigma non-opioid intracellular receptor 1
Omim ID
601978Gene Ontology
HyperlinkGene Summary
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000000515|OTTHUMP00000000516|OTTHUMP00000000517|OTTHUMP00000021286|SR31747 binding protein 1|aging-associated gene 8 protein|opioid receptor, sigma 1|sigma1 receptor|type I sigma receptor
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Interactome
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Disease
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