OGFR polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant OGFR.
Immunogen
Recombinant protein corresponding to amino acids of human OGFR.
Sequence
RRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPA
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human liver with OGFR polyclonal antibody (Cat # PAB20975) shows nuclear positivity in hepatocytes at 1:50-1:200 dilution. -
Gene Info — OGFR
Entrez GeneID
11054Protein Accession#
Q9NZT2Gene Name
OGFR
Gene Alias
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Gene Description
opioid growth factor receptor
Omim ID
606459Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported. [provided by RefSeq
Other Designations
7-60 protein|OTTHUMP00000031503|zeta-type opioid receptor
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Interactome
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Publication Reference
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Exogenous OGF enhances the anti-tumor activity of cisplatin on hepatocellular carcinoma.
Yinhe Sikong, Qing Wang, Meijuan Cai, Aijun Zhang, Fei Pang, Xiangdan Cui.
International Journal of Clinical and Experimental Pathology 2019 Feb; 12(2):590.
Application:IHC-P, WB-Ti, WB-Tr, Human, Human hepatocellular carcinoma, SK-Hep1 cells.
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Exogenous OGF enhances the anti-tumor activity of cisplatin on hepatocellular carcinoma.
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