TREML1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant TREML1.
Immunogen
Recombinant protein corresponding to amino acids of human TREML1.
Sequence
APVGSSILVQCHYRLQDVKAQKVWCRFLPEGCQPLVSSAVDRRAPAGRRTFLTDLGGGLLQVEMVTLQEEDAGEYGCMVDGARGPQILHRVSLNILPPEEEEETHKIGSLAENAFSDPAGSANPLEPSQD
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells) with TREML1 polyclonal antibody (Cat # PAB20967).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human bone marrow with TREML1 polyclonal antibody (Cat # PAB20967) shows strong positivity in megakaryocytes. -
Gene Info — TREML1
Entrez GeneID
340205Protein Accession#
Q86YW5Gene Name
TREML1
Gene Alias
GLTL1825, MGC119173, PRO3438, TLT-1, TLT1, dJ238O23.3
Gene Description
triggering receptor expressed on myeloid cells-like 1
Omim ID
609714Gene Ontology
HyperlinkGene Summary
TREML1 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties. TREML1 enhances calcium signaling in an SHP2 (PTPN11; MIM 176876)-dependent manner (Allcock et al., 2003 [PubMed 12645956]; Barrow et al., 2004 [PubMed 15128762]).[supplied by OMIM
Other Designations
OTTHUMP00000017858|TREM-like transcript 1
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