SCN4B polyclonal antibody
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Specifications
Product Description
Rabbit polyclonal antibody raised against recombinant SCN4B.
Immunogen
Recombinant protein corresponding to amino acids of human SCN4B.
Sequence
LLPCTFSSCFGFEDLHFRWTYNSSDAFKILIEGTVKNEKSDPKVTLKDDDRITLVGSTKEKMNNISIVLRDLEFSDTGKYTCHVKNPKENNLQHHATIFLQVV
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human small intestine with SCN4B polyclonal antibody (Cat # PAB20936) shows moderate positivity in glandular cells. -
Gene Info — SCN4B
Entrez GeneID
6330Protein Accession#
Q8IWT1Gene Name
SCN4B
Gene Alias
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Gene Description
sodium channel, voltage-gated, type IV, beta
Omim ID
608256Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene
Other Designations
sodium channel beta-4 subunit
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Interactomes
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Diseases
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