FUCA2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of FUCA2.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human FUCA2.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Western Blot (1:1000)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of FUCA2 (arrow) using FUCA2 polyclonal antibody (Cat # PAB2090). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FUCA2 gene (Lane 2) (Origene Technologies).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human hepatocellular carcinoma reacted with FUCA2 polyclonal antibody (Cat # PAB2090) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. -
Gene Info — FUCA2
Entrez GeneID
2519Protein Accession#
NP_114409;Q9BTY2Gene Name
FUCA2
Gene Alias
MGC1314, dJ20N2.5
Gene Description
fucosidase, alpha-L- 2, plasma
Omim ID
136820Gene Ontology
HyperlinkGene Summary
alpha-L- 2
Other Designations
OTTHUMP00000017331
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Interactome
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Pathway
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Publication Reference
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The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A.
Genome Research 2003 Sep; 13(10):2265.
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Linkage of plasma alpha-L-fucosidase (FUCA2) and the plasminogen (PLG) system.
Eiberg H, Mohr J, Nielsen LS.
Clinical Genetics 1984 Jul; 26(1):23.
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The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
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