WNT7A polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant WNT7A.
Immunogen
Recombinant protein corresponding to amino acids of human WNT7A.
Sequence
ILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRACNKTAPQ
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with WNT7A polyclonal antibody (Cat # PAB20839).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human testis with WNT7A polyclonal antibody (Cat # PAB20839) shows strong membrane and cytoplasmic positivity in cells in seminiferus ducts. -
Gene Info — WNT7A
Entrez GeneID
7476Protein Accession#
O00755Gene Name
WNT7A
Gene Alias
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Gene Description
wingless-type MMTV integration site family, member 7A
Gene Ontology
HyperlinkGene Summary
This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes. [provided by RefSeq
Other Designations
proto-oncogene Wnt7a protein
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Interactome
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Pathway
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Disease
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